Thursday, November 21, 2002
Just like any other medication, Gonal-F may cause unwanted effects. For most people these are mild and cease once therapy is stopped. Therefore the benefits of Gonal-F treatment far outweigh the risk of unwanted effects for most people.
Shortly after treatment is commenced with Gonal-F, the following effects may be seen or experienced: enlargement of the ovaries, abdominal pain, ovarian cysts, ovarian hyperstimulation syndrome, nausea, vomiting, abdominal cramps, bloating, diarrhoea, pain, redness or swelling at the injection site, breast tenderness, dry skin or hair loss.
In very rare cases a clot may form in a blood vessel, this will usually be associated with severe ovarian hyperstimulation syndrome or OHSS (see overdosage below).
Multiple pregnancies such as twins and in rare cases, triplets, sometimes result from assisted conception and may affect the outcome of pregnancies and the health of the new born babies. As with any pregnancy, complications may occur, such as ectopic pregnancy (pregnancy outside of the womb), miscarriage, stillbirth and birth defects.
All drugs, including Gonal-F, carry the risk of possible unwanted effects. You must consult your doctor, pharmacist or nurse if you experience any unwanted effects while taking Gonal-F.
What do I do if I suspect overdosage?
Hyperstimulation of the ovaries, known as ovarian hyperstimulation syndrome (OHSS) is a rare, but potentially serious complication of infertility therapy and can be the result of excessive doses of Gonal-F. Without proper hospital management, this condition may even be fatal. The initial symptoms may consist of lower abdominal pain, abdominal swelling and/or nausea and vomiting. Should one or more of these symptoms develop, you must consult your doctor immediately. The risk of producing the syndrome may be greatly reduced by adequate patient monitoring during therapy, and by correct adjustment of the medicine.
Shortly after treatment is commenced with Gonal-F, the following effects may be seen or experienced: enlargement of the ovaries, abdominal pain, ovarian cysts, ovarian hyperstimulation syndrome, nausea, vomiting, abdominal cramps, bloating, diarrhoea, pain, redness or swelling at the injection site, breast tenderness, dry skin or hair loss.
In very rare cases a clot may form in a blood vessel, this will usually be associated with severe ovarian hyperstimulation syndrome or OHSS (see overdosage below).
Multiple pregnancies such as twins and in rare cases, triplets, sometimes result from assisted conception and may affect the outcome of pregnancies and the health of the new born babies. As with any pregnancy, complications may occur, such as ectopic pregnancy (pregnancy outside of the womb), miscarriage, stillbirth and birth defects.
All drugs, including Gonal-F, carry the risk of possible unwanted effects. You must consult your doctor, pharmacist or nurse if you experience any unwanted effects while taking Gonal-F.
What do I do if I suspect overdosage?
Hyperstimulation of the ovaries, known as ovarian hyperstimulation syndrome (OHSS) is a rare, but potentially serious complication of infertility therapy and can be the result of excessive doses of Gonal-F. Without proper hospital management, this condition may even be fatal. The initial symptoms may consist of lower abdominal pain, abdominal swelling and/or nausea and vomiting. Should one or more of these symptoms develop, you must consult your doctor immediately. The risk of producing the syndrome may be greatly reduced by adequate patient monitoring during therapy, and by correct adjustment of the medicine.
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